Anti-IDH1 Polyclonal Antibody (HF781014)

Name: Anti-IDH1 Polyclonal Antibody
Brand: abinScience
SKU: HF781014
Price: 168 USD
Availability: InStock

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100ug

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Aperçu

Numéro de catalogue

HF781014

Description

Anti-IDH1 Polyclonal Antibody (HF781014) is a rabbit polyclonal antibody detecting IDH1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Microtus mexicanus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human IDH1 (Met1-Leu414).

Cible

IDH1, IDH, NADP(+)-specific ICDH, Isocitrate dehydrogenase [NADP] cytoplasmic, PICD, IDP, Cytosolic NADP-isocitrate dehydrogenase, Oxalosuccinate decarboxylase

Purification

Purified by antigen affinity column.

Numéro d'accès

O75874

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) is a ~46 kDa protein. Catalyzes the NADP(+)-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglutarate), which is required by other enzymes such as the phytanoyl-CoA dioxygenase. Plays a critical role in the generation of NADPH, an important cofactor in many biosynthesis pathways. May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency.

1. Geisbrecht, BV. et al. (1999) The Journal of biological chemistry 274, 30527-33. PMID: 10521434

2. Dang, L. et al. (2009) Nature 462, 739-44. PMID: 19935646

Note

For research use only.

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