

| Número de catálogo | HV609014 | ||||||||
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| Descripción |
Anti-IFNL1/IL29 Polyclonal Antibody (HV609014) is a rabbit polyclonal antibody detecting IFNL1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human IFNL1/IL29 (Gly20-Thr200). | ||||||||
| Objetivo | ZCYTO21, Cytokine Zcyto21, IFNL1, Interferon lambda-1, IL-29, IFN-lambda-1, Interleukin-29, IL29 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q8IU54 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Interferon lambda-1 (IL29/IFNL1) is a ~21 kDa protein. Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression. | ||||||||
| Nota | For research use only. |
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