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Anti-IGF2BP2 Polyclonal Antibody (HV403014)

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Vista general
Número de catálogoHV403014
Descripción
Anti-IGF2BP2 Polyclonal Antibody (HV403014) is a rabbit polyclonal antibody detecting IGF2BP2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Pongo abelii.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human IGF2BP2 (Ser141-Pro384).
Objetivo Hepatocellular carcinoma autoantigen p62, IMP2, IGF-II mRNA-binding protein 2, IMP-2, VICKZ2, VICKZ family member 2, IGF2BP2, IGF2 mRNA-binding protein 2, Insulin-like growth factor 2 mRNA-binding protein 2
Purificación Purified by antigen affinity column.
Número de acceso Q9Y6M1
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is a ~66 kDa protein. RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Preferentially binds to N6-methyladenosine (m6A)-containing mRNAs and increases their stability. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs.

1. Huang, H. et al. (2018) Nature cell biology 20, 285-295. PMID: 29476152
2. Nielsen, J. et al. (1999) Molecular and cellular biology 19, 1262-70. PMID: 9891060
Nota For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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