Anti-IGF2BP2 Polyclonal Antibody (HV403014)

Name: Anti-IGF2BP2 Polyclonal Antibody
Brand: abinScience
SKU: HV403014
Price: 168 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HV403014

説明

Anti-IGF2BP2 Polyclonal Antibody (HV403014) is a rabbit polyclonal antibody detecting IGF2BP2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human, Mouse

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human IGF2BP2 (Ser141-Pro384).

ターゲット

Hepatocellular carcinoma autoantigen p62, IMP2, IGF-II mRNA-binding protein 2, IMP-2, VICKZ2, VICKZ family member 2, IGF2BP2, IGF2 mRNA-binding protein 2, Insulin-like growth factor 2 mRNA-binding protein 2

精製

Purified by antigen affinity column.

アクセッション番号

Q9Y6M1

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is a ~66 kDa protein. RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Preferentially binds to N6-methyladenosine (m6A)-containing mRNAs and increases their stability. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs.

1. Huang, H. et al. (2018) Nature cell biology 20, 285-295. PMID: 29476152

2. Nielsen, J. et al. (1999) Molecular and cellular biology 19, 1262-70. PMID: 9891060

注意事項

For research use only.

イメージ

参考文献

データシート

Anti-IGF2BP2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-IGF2BP2 Polyclonal Antibody (HV403014)

概要

イメージ

参考文献

データシート

SDS

クイックアクセス

お問い合わせ