Anti-IGF2BP2 Polyclonal Antibody (HV403014)

Name: Anti-IGF2BP2 Polyclonal Antibody
Brand: abinScience
SKU: HV403014
Price: 168 USD
Availability: InStock

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Обзор

Каталожный номер

HV403014

Описание

Anti-IGF2BP2 Polyclonal Antibody (HV403014) is a rabbit polyclonal antibody detecting IGF2BP2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human IGF2BP2 (Ser141-Pro384).

Цель

Hepatocellular carcinoma autoantigen p62, IMP2, IGF-II mRNA-binding protein 2, IMP-2, VICKZ2, VICKZ family member 2, IGF2BP2, IGF2 mRNA-binding protein 2, Insulin-like growth factor 2 mRNA-binding protein 2

Очистка

Purified by antigen affinity column.

Номер доступа

Q9Y6M1

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is a ~66 kDa protein. RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Preferentially binds to N6-methyladenosine (m6A)-containing mRNAs and increases their stability. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs.

1. Huang, H. et al. (2018) Nature cell biology 20, 285-295. PMID: 29476152

2. Nielsen, J. et al. (1999) Molecular and cellular biology 19, 1262-70. PMID: 9891060

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-IGF2BP2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

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