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Anti-IGHMBP2 Polyclonal Antibody (HA628014)

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Aperçu
Numéro de catalogueHA628014
Description
Anti-IGHMBP2 Polyclonal Antibody (HA628014) is a rabbit polyclonal antibody detecting DNA-binding protein SMUBP-2; 3.6.4.12; 3.6.4.13; ATP-dependent helicase IGHMBP2; Glial factor 1; GF-1; Immunoglobulin mu-binding protein 2; IGHMBP2; SMBP2; SMUBP2 in ELISA, IHC, WB. Suitable for Human, Rat, and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant human IGHMBP2 (Met1-Val440).
Cible DNA-binding protein SMUBP-2; 3.6.4.12; 3.6.4.13; ATP-dependent helicase IGHMBP2; Glial factor 1; GF-1; Immunoglobulin mu-binding protein 2; IGHMBP2; SMBP2; SMUBP2
Niveau d'endotoxines Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Numéro d'accès P38935, Q9EQN5, P40694
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

DNA-binding protein SMUBP-2 (IGHMBP2) is a ~109 kDa protein. 5' to 3' helicase that unwinds RNA and DNA duplexes in an ATP-dependent reaction. Specific to 5'-phosphorylated single-stranded guanine-rich sequences. May play a role in RNA metabolism, ribosome biogenesis or initiation of translation. May play a role in regulation of transcription. Interacts with tRNA-Tyr.

1. Guenther, UP. et al. (2009) Human molecular genetics 18, 1288-300. PMID: 19158098
2. Jaudzems, K. et al. (2012) Journal of molecular biology 424, 42-53. PMID: 22999958
3. Kanaan, J. et al. (2018) Nature communications 9, 3752. PMID: 30218034
4. Fukita, Y. et al. (1993) The Journal of biological chemistry 268, 17463-70. PMID: 8349627
5. de Planell-Saguer, M. et al. (2009) Human molecular genetics 18, 2115-26. PMID: 19299493
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-IGHMBP2 Polyclonal Antibody

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