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Anti-ST2/IL-33R Recombinant Antibody (TQC2938) (TQC2938) (HX139043)

Anti-ST2/IL-33R Recombinant Antibody (TQC2938) (TQC2938)
Anti-ST2/IL-33R Recombinant Antibody (TQC2938) (TQC2938)
Цена(USD):
Спецификация:
  • 50ug
  • 100ug
  • 1mg
Количество:
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  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерHX139043
Реактивность видовHuman
ПримененияELISA
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG2-kappa
ID клонаTQC2938
Цель Interleukin-1 receptor-like 1, EC:3.2.2.6, Protein ST2, IL1RL1, DER4, ST2, T1
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа Q01638
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4

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Информация об использовании продукта
Применение Разбавление
ELISA 1:2000-1:20000
Фон

Interleukin-1 receptor-like 1 (IL1RL1/ST2) is a ~63 kDa protein. Receptor for interleukin-33 (IL-33) which plays crucial roles in innate and adaptive immunity, contributing to tissue homeostasis and responses to environmental stresses together with coreceptor IL1RAP. Its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function (Probable). Upon tissue injury, induces UCP2-dependent mitochondrial rewiring that attenuates the generation of reactive oxygen species and preserves the integrity of Krebs cycle required for persistent production of itaconate and subsequent GATA3-dependent differentiation of inflammation-resolving alternatively activated macrophages.

1. Yi, XM. et al. (2022) Proceedings of the National Academy of Sciences of the United States of America 119, e2116279119. PMID: 35238669
2. Schmitz, J. et al. (2005) Immunity 23, 479-90. PMID: 16286016
Примечание For research use only
Изображения
  • Anti-ST2/IL-33R Recombinant Antibody (TQC2938) (TQC2938)

    SDS-PAGE

    SDS-PAGE for Anti-IL1RL1/ST2 Antibody (TQC2938) (TQC2938)

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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