Anti-Mouse IL-33 Polyclonal Antibody (MF543014)

Name: Anti-Mouse IL-33 Polyclonal Antibody
Brand: abinScience
SKU: MF543014
Price: 168 USD
Availability: InStock

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Reférences
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SDS

Aperçu

Numéro de catalogue

MF543014

Description

Anti-IL33 Polyclonal Antibody (MF543014) is a rabbit polyclonal antibody detecting Il33 in ELISA, IHC, WB. Suitable for Mus musculus and Rattus norvegicus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Mouse

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Mouse IL33 (Ser109-Ile266).

Cible

Interleukin-33, IL-33, Interleukin-33(102-266), Interleukin-33(109-266), Il33

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

Q8BVZ5, Q66H70

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Interleukin-33 (IL33) is a ~29 kDa protein. Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as an enhancer of polarization of alternatively activated macrophages. Acts as a chemoattractant for Th2 cells, and may function as an 'alarmin', that amplifies immune responses during tissue injury.

1. Osbourn, M. et al. (2017) Immunity 47, 739-751.e5. PMID: 29045903

2. Faas, M. et al. (2021) Immunity 54, 2531-2546.e5. PMID: 34644537

Note

For research use only

Images

Reférences

Fiche technique

Anti-Mouse IL-33 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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