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| カタログ番号 | MF543014 | ||||||||
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| 説明 |
Anti-IL33 Polyclonal Antibody (MF543014) is a rabbit polyclonal antibody detecting Il33 in ELISA, IHC, WB. Suitable for Mus musculus and Rattus norvegicus.
Highlights
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| 種反応性 | Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse IL33 (Ser109-Ile266). | ||||||||
| ターゲット | Interleukin-33, IL-33, Interleukin-33(102-266), Interleukin-33(109-266), Il33 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q8BVZ5, Q66H70 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Interleukin-33 (IL33) is a ~29 kDa protein. Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as an enhancer of polarization of alternatively activated macrophages. Acts as a chemoattractant for Th2 cells, and may function as an 'alarmin', that amplifies immune responses during tissue injury. 1. Osbourn, M. et al. (2017) Immunity 47, 739-751.e5. PMID: 29045903 2. Faas, M. et al. (2021) Immunity 54, 2531-2546.e5. PMID: 34644537 | ||||||||
| 注意事項 | For research use only |
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