中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HA692014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-IMPA1 Polyclonal Antibody (HA692014) is a rabbit polyclonal antibody detecting Inositol monophosphatase 1; IMP 1; IMPase 1; 3.1.3.25; D-galactose 1-phosphate phosphatase; 3.1.3.94; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; IMPA1; IMPA in ELISA, IHC, WB. Suitable for Human, Bovine, Mouse, and Pig.
Highlights
|
||||||||
| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human IMPA1 (Met1-Asp277). | ||||||||
| ターゲット | Inositol monophosphatase 1; IMP 1; IMPase 1; 3.1.3.25; D-galactose 1-phosphate phosphatase; 3.1.3.94; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; IMPA1; IMPA | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P29218, P20456, O55023, O77591 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||||||
| 製品使用情報 |
| ||||||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Inositol monophosphatase 1 (IMPA1) is a ~30 kDa protein. Phosphatase involved in the dephosphorylation of myo-inositol monophosphates to generate myo-inositol. Is also able to dephosphorylate scyllo-inositol-phosphate, myo-inositol 1,4-diphosphate, scyllo-inositol-1,3-diphosphate and scyllo-inositol-1,4-diphosphate. Also dephosphorylates in vitro other sugar-phosphates including D-galactose-1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate and 2'-AMP. Responsible for the provision of inositol required for synthesis of phosphatidylinositols and polyphosphoinositides, and involved in maintaining normal brain function. Has been implicated as the pharmacological target for lithium (Li(+)) action in brain, which is used to treat bipolar affective disorder. 1. Ohnishi, T. et al. (2007) The Journal of biological chemistry 282, 637-46. PMID: 17068342 2. Ganzhorn, AJ. et al. (1996) Biochemistry 35, 10957-66. PMID: 8718889 3. Parthasarathy, R. et al. (1997) Brain research 778, 99-106. PMID: 9462881 4. Figueiredo, T. et al. (2016) Molecular psychiatry 21, 1125-9. PMID: 26416544 | ||||||||
| 注意事項 | For research use only |
お問い合わせ
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
