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| カタログ番号 | VK736023 | ||||||
|---|---|---|---|---|---|---|---|
| 種反応性 | Influenza A virus (H1N1) | ||||||
| アプリケーション | ELISA, FCM, IF, WB | ||||||
| 宿主種 | Human | ||||||
| クローン性 | Monoclonal | ||||||
| アイソタイプ | IgG1 | ||||||
| クローンID | SAA1442 | ||||||
| ターゲット | Matrix protein 2, Proton channel protein M2, M | ||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||
| 純度 | >95% as determined by SDS-PAGE. | ||||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||||
| アクセッション番号 | P06821 | ||||||
| RRID | Anti-Influenza A virus M/Matrix protein 2 Antibody (SAA1442) (abinScience Cat# VK736023, RRID:AB_3727015) |
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| 形態 | Liquid | ||||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| 背景 | Matrix protein 2 is a ~11 kDa protein. Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome triggers M2 ion channel activity. The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur. Also plays a role in viral proteins secretory pathway. | ||||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Influenza A virus M/Matrix protein 2 Antibody (SAA1442)
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