

| Numéro de catalogue | VK560013 | ||||
|---|---|---|---|---|---|
| Description |
Anti-Influenza A virus RNA polymerase complex Nanobody (SAA1427) [SAA1427] (VK560013) is a alpaca monoclonal antibody detecting RNA-directed RNA polymerase subunit P2 in ELISA.
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| Reactivité des espèces | Influenza A virus (H3N2) | ||||
| Applications | ELISA | ||||
| Espèce hôte | Alpaca | ||||
| Clonalité | Monoclonal | ||||
| Isotype | VHH-8His-Cys-tag | ||||
| ID de clone | SAA1427 | ||||
| Cible | Polymerase acidic protein, 3.1.-.-, RNA-directed RNA polymerase subunit P2, PA | ||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Purified by Nickel column. | ||||
| Numéro d'accès | P03434 | ||||
| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Contexte | Polymerase acidic protein (RNA polymerase complex) is a ~82 kDa protein. Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity. | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Influenza A virus RNA polymerase complex Recombinant Nanobody (SAA1427)
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