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| カタログ番号 | VK560013 | ||||
|---|---|---|---|---|---|
| 説明 |
Anti-Influenza A virus RNA polymerase complex Nanobody (SAA1427) [SAA1427] (VK560013) is a alpaca monoclonal antibody detecting RNA-directed RNA polymerase subunit P2 in ELISA.
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| 種反応性 | Influenza A virus (H3N2) | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Alpaca | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | VHH-8His-Cys-tag | ||||
| クローンID | SAA1427 | ||||
| ターゲット | Polymerase acidic protein, 3.1.-.-, RNA-directed RNA polymerase subunit P2, PA | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Purified by Nickel column. | ||||
| アクセッション番号 | P03434 | ||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Polymerase acidic protein (RNA polymerase complex) is a ~82 kDa protein. Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity. | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Influenza A virus RNA polymerase complex Recombinant Nanobody (SAA1427)
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