

| Numéro de catalogue | VK560023 | ||||
|---|---|---|---|---|---|
| Description |
Anti-Influenza A virus RNA polymerase complex Nanobody (SAA2270) [SAA2270] (VK560023) is a alpaca monoclonal antibody detecting RNA-directed RNA polymerase subunit P2 in ELISA. Suitable for Influenza A virus.
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| Reactivité des espèces | Influenza A virus | ||||
| Applications | ELISA | ||||
| Espèce hôte | Alpaca | ||||
| Clonalité | Monoclonal | ||||
| Isotype | VHH-His | ||||
| ID de clone | SAA2270 | ||||
| Cible | Polymerase acidic protein, RNA-directed RNA polymerase subunit P2, PA | ||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||
| Pureté | >90% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Numéro d'accès | P03427 | ||||
| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Contexte | Polymerase basic protein 2 (RNA polymerase complex) is a ~85 kDa protein. Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription. Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA. Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex. In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS. | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Influenza A virus RNA polymerase complex Nanobody (SAA2270)
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