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| カタログ番号 | VK560023 | ||||
|---|---|---|---|---|---|
| 説明 |
Anti-Influenza A virus RNA polymerase complex Nanobody (SAA2270) [SAA2270] (VK560023) is a alpaca monoclonal antibody detecting RNA-directed RNA polymerase subunit P2 in ELISA. Suitable for Influenza A virus.
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| 種反応性 | Influenza A virus | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Alpaca | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | VHH-His | ||||
| クローンID | SAA2270 | ||||
| ターゲット | Polymerase acidic protein, RNA-directed RNA polymerase subunit P2, PA | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >90% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | P03427 | ||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Polymerase basic protein 2 (RNA polymerase complex) is a ~85 kDa protein. Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription. Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA. Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex. In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS. | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Influenza A virus RNA polymerase complex Nanobody (SAA2270)
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中国武漢市深敦寺路666号C棟、武漢、430206
