

| Número de catálogo | HW565014 | ||||||||
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| Descripción |
Anti-IREB2 Polyclonal Antibody (HW565014) is a rabbit polyclonal antibody detecting IREB2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Pig.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human IREB2 (Pro39-Ser281). | ||||||||
| Objetivo | IRP2, Iron-responsive element-binding protein 2, IREB2, IRE-BP 2, Iron regulatory protein 2 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P48200 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Iron-responsive element-binding protein 2 (IREB2) is a ~105 kDa protein. RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA. | ||||||||
| Nota | For research use only. |
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