

| Numéro de catalogue | HW565014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-IREB2 Polyclonal Antibody (HW565014) is a rabbit polyclonal antibody detecting IREB2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Pig.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human IREB2 (Pro39-Ser281). | ||||||||
| Cible | IRP2, Iron-responsive element-binding protein 2, IREB2, IRE-BP 2, Iron regulatory protein 2 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P48200 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Iron-responsive element-binding protein 2 (IREB2) is a ~105 kDa protein. RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA. | ||||||||
| Note | For research use only. |
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