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| カタログ番号 | HX843014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-IRF9 Polyclonal Antibody (HX843014) is a rabbit polyclonal antibody detecting IRF9 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human IRF9 (Met1-Val393). | ||||||||
| ターゲット | Interferon regulatory factor 9, ISGF3G, IRF-9, ISGF-3 gamma, ISGF3 p48 subunit, Transcriptional regulator ISGF3 subunit gamma, IRF9, Interferon-stimulated gene factor 3 gamma, IFN-alpha-responsive transcription factor subunit | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q00978 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Interferon regulatory factor 9 (IRF9) is a ~43 kDa protein. Transcription factor that plays an essential role in anti-viral immunity. It mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. | ||||||||
| 注意事項 | For research use only. |
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