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| カタログ番号 | HV600014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-ITLN1 Polyclonal Antibody (HV600014) is a rabbit polyclonal antibody detecting ITLN1 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human ITLN1 (Cys31-Gly253). | ||||||||
| ターゲット | INTL, ITLN-1, Intestinal lactoferrin receptor, ITLN, LFR, Intelectin-1, ITLN1, Omentin, Galactofuranose-binding lectin, Endothelial lectin HL-1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q8WWA0 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Intelectin-1 (ITLN1) is a ~34 kDa protein. Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner. Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO). Binds to glycans from Gram-positive and Gram-negative bacteria, including K.pneumoniae, S.pneumoniae, Y.pestis, P.mirabilis and P.vulgaris. Does not bind human glycans. Probably plays a role in the defense system against microorganisms (Probable). 1. Tsuji, S. et al. (2001) The Journal of biological chemistry 276, 23456-63. PMID: 11313366 2. Wesener, DA. et al. (2015) Nature structural & molecular biology 22, 603-10. PMID: 26148048 3. Yang, RZ. et al. (2006) American journal of physiology. Endocrinology and metabolism 290, E1253-61. PMID: 16531507 4. Suzuki, YA. et al. (2001) Biochemistry 40, 15771-9. PMID: 11747454 5. Akiyama, Y. et al. (2013) Journal of biochemistry 154, 437-48. PMID: 23921499 | ||||||||
| 注意事項 | For research use only. |
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