

| Numéro de catalogue | HF563014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-KATNA1 Polyclonal Antibody (HF563014) is a rabbit polyclonal antibody detecting KATNA1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Macaca fascicularis.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human KATNA1 (Met1-Lys167). | ||||||||
| Cible | Katanin p60 ATPase-containing subunit A1, p60 katanin, KATNA1, Katanin p60 subunit A1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O75449 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Katanin p60 ATPase-containing subunit A1 (KATNA1) is a ~55 kDa protein. Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth. | ||||||||
| Note | For research use only. |
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