

| Número de catálogo | HC698024 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-KIF5A Polyclonal Antibody (HC698024) is a rabbit polyclonal antibody detecting KIF5A in ELISA, IHC, WB. Suitable for Human, Mouse, Pongo abelii, and Rat.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human KIF5A (Met1-Ala331). | ||||||||
| Objetivo | NKHC1, KIF5A, Kinesin heavy chain isoform 5A, Neuronal kinesin heavy chain, Kinesin heavy chain neuron-specific 1, NKHC | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q12840 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Kinesin heavy chain isoform 5A (KIF5A) is a ~117 kDa protein. Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL). Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. The ZFYVE27-KIF5A complex contributes to the vesicular transport of VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 proteins in neurons. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation. | ||||||||
| Nota | For research use only. |
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