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Anti-Human KISS1R Polyclonal Antibody (HV546014)

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Aperçu
Numéro de catalogueHV546014
Description
Anti-KISS1R Polyclonal Antibody (HV546014) is a rabbit polyclonal antibody detecting KISS1R in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesHuman
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human KISS1R (His2-Trp43).
Cible KiSS-1R, G-protein coupled receptor 54, KiSS-1 receptor, GPR54, KISS1R, hOT7T175, G-protein coupled receptor OT7T175, Metastin receptor, Hypogonadotropin-1, AXOR12, Kisspeptins receptor
Purification Purified by antigen affinity column.
Numéro d'accès Q969F8
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

KiSS-1 receptor (KISS1R) is a ~42 kDa protein. Receptor for kisspeptins (kisspeptin-10, kisspeptin-13, kisspeptin-14 and metastin/kisspeptin-54). The hypothalamic KISS1/KISS1R signaling system plays a central role in the regulation of the hypothalamic-pituitary-gonadal reproductive axis by modulating the secretion of gonadotropin-releasing hormone (GnRH) from GnRH neurons. In these neurons, kisspeptin binding to its receptor activates G(q)-dependent signaling, leading to phospholipase C (PLC) activation, and hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2). The subsequent rise in intracellular calcium levels results in the inhibition of inward rectifier potassium channels and activation of TRPC-like cation channels, leading to GnRH neurons depolarization and stimulation. In addition to this pathway, kisspeptin also triggers G(q)-independent signaling via beta-arrestin, leading to MAPK cascade activation and ERK1/ERK2 phosphorylation.

1. Kotani, M. et al. (2001) The Journal of biological chemistry 276, 34631-6. PMID: 11457843
2. Hori, A. et al. (2001) Biochemical and biophysical research communications 286, 958-63. PMID: 11527393
3. Bilban, M. et al. (2004) Journal of cell science 117, 1319-28. PMID: 15020672
4. Becker, JA. et al. (2005) Biochemical and biophysical research communications 326, 677-86. PMID: 15596153
5. de Roux, N. et al. (2003) Proceedings of the National Academy of Sciences of the United States of America 100, 10972-6. PMID: 12944565
6. Seminara, SB. et al. (2003) The New England journal of medicine 349, 1614-27. PMID: 14573733
7. Semple, RK. et al. (2005) The Journal of clinical endocrinology and metabolism 90, 1849-55. PMID: 15598687
8. Tenenbaum-Rakover, Y. et al. (2007) The Journal of clinical endocrinology and metabolism 92, 1137-44. PMID: 17164310
9. Teles, MG. et al. (2008) The New England journal of medicine 358, 709-15. PMID: 18272894
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human KISS1R Polyclonal Antibody

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