

| Numéro de catalogue | HW573014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-KLK7 Polyclonal Antibody (HW573014) is a rabbit polyclonal antibody detecting KLK7 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human KLK7 (Glu23-Arg253). | ||||||||
| Cible | hSCCE, Stratum corneum chymotryptic enzyme, PRSS6, Kallikrein-7, Serine protease 6, hK7, KLK7, SCCE | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P49862 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Kallikrein-7 (KLK7) is a ~27 kDa protein. May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines. | ||||||||
| Note | For research use only. |



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