

| Numéro de catalogue | HB144014 | ||||||||
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| Description |
Anti-LAP3 Polyclonal Antibody (HB144014) is a rabbit polyclonal antibody detecting LAP3 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pig.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human LAP3 (Ala320-Ala519). | ||||||||
| Cible | LAPEP, PEPS, Cysteinylglycine-S-conjugate dipeptidase, LAP3, Leucyl aminopeptidase, LAP-3, Prolyl aminopeptidase, Peptidase S, Cytosol aminopeptidase, Leucine aminopeptidase 3, Proline aminopeptidase | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P28838 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Cytosol aminopeptidase (LAP3) is a ~56 kDa protein. Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status. | ||||||||
| Note | For research use only. |
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