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| カタログ番号 | HB144014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-LAP3 Polyclonal Antibody (HB144014) is a rabbit polyclonal antibody detecting LAP3 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pig.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human LAP3 (Ala320-Ala519). | ||||||||
| ターゲット | LAPEP, PEPS, Cysteinylglycine-S-conjugate dipeptidase, LAP3, Leucyl aminopeptidase, LAP-3, Prolyl aminopeptidase, Peptidase S, Cytosol aminopeptidase, Leucine aminopeptidase 3, Proline aminopeptidase | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P28838 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Cytosol aminopeptidase (LAP3) is a ~56 kDa protein. Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status. | ||||||||
| 注意事項 | For research use only. |
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