Anti-LASV GPC Polyclonal Antibody (VK453014)

Name: Anti-LASV GPC Polyclonal Antibody
Brand: abinScience
SKU: VK453014
Price: 168 USD
Availability: InStock

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Spécification :

50ug
100ug

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Aperçu
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Reférences
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SDS

Aperçu

Numéro de catalogue

VK453014

Description

Anti-Lassa virus/LASV GPC Polyclonal Antibody (VK453014) is a rabbit polyclonal antibody detecting GPC in ELISA, IHC, WB. Suitable for Lassa virus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Lassa virus (LASV)

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Lassa virus/LASV GPC (Thr59-Leu259).

Applications testées

Cible

Pre-glycoprotein polyprotein GP complex, Pre-GP-C, Stable signal peptide, SSP, Glycoprotein G1, GP1, Glycoprotein G2, GP2, GPC, GP-C

Purification

Purified by antigen affinity column.

Numéro d'accès

P08669

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Pre-glycoprotein polyprotein GP complex (GPC) is a ~55 kDa protein. Functions as a cleaved signal peptide that is retained as the third component of the GP complex (GP-C). Helps to stabilize the spike complex in its native conformation. The SSP is required for efficient glycoprotein expression, post-translational maturation cleavage of G1 and G2, glycoprotein transport to the cell surface plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion.

1. Katz, M. et al. (2022) Nature 603, 174-179. PMID: 35173332

2. Eichler, R. et al. (2003) EMBO reports 4, 1084-8. PMID: 14555961

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-LASV-GP1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant Lassa virus/LASV GPC (Catalog No: VK453012)

Reférences

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