

| Каталожный номер | VK453014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Lassa virus/LASV GPC Polyclonal Antibody (VK453014) is a rabbit polyclonal antibody detecting GPC in ELISA, IHC, WB. Suitable for Lassa virus.
Highlights
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| Реактивность видов | Lassa virus (LASV) | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Lassa virus/LASV GPC (Thr59-Leu259). | ||||||||
| Проверенные приложения | WB | ||||||||
| Цель | Pre-glycoprotein polyprotein GP complex, Pre-GP-C, Stable signal peptide, SSP, Glycoprotein G1, GP1, Glycoprotein G2, GP2, GPC, GP-C | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P08669 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Pre-glycoprotein polyprotein GP complex (GPC) is a ~55 kDa protein. Functions as a cleaved signal peptide that is retained as the third component of the GP complex (GP-C). Helps to stabilize the spike complex in its native conformation. The SSP is required for efficient glycoprotein expression, post-translational maturation cleavage of G1 and G2, glycoprotein transport to the cell surface plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion. 1. Katz, M. et al. (2022) Nature 603, 174-179. PMID: 35173332 2. Eichler, R. et al. (2003) EMBO reports 4, 1084-8. PMID: 14555961 | ||||||||
| Примечание | For research use only. |

Western blot analysis was performed using anti-LASV-GP1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant Lassa virus/LASV GPC (Catalog No: VK453012)




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