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| カタログ番号 | VK453024 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Lassa virus/LASV GPC Polyclonal Antibody (VK453024) is a rabbit polyclonal antibody detecting GPC in ELISA, IHC, WB. Suitable for Lassa virus.
Highlights
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| 種反応性 | Lassa virus (LASV) | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Lassa virus/LASV GPC (Gly260-Asp432). | ||||||||
| テスト済みアプリケーション | WB | ||||||||
| ターゲット | Pre-glycoprotein polyprotein GP complex, Pre-GP-C, Stable signal peptide, SSP, Glycoprotein G1, GP1, Glycoprotein G2, GP2, GPC, GP-C | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P08669 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Pre-glycoprotein polyprotein GP complex (GPC) is a ~55 kDa protein. Functions as a cleaved signal peptide that is retained as the third component of the GP complex (GP-C). Helps to stabilize the spike complex in its native conformation. The SSP is required for efficient glycoprotein expression, post-translational maturation cleavage of G1 and G2, glycoprotein transport to the cell surface plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion. 1. Katz, M. et al. (2022) Nature 603, 174-179. PMID: 35173332 2. Eichler, R. et al. (2003) EMBO reports 4, 1084-8. PMID: 14555961 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-RSV-GP2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant Lassa virus/LASV GPC (Catalog No: VK453022)
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中国武漢市深敦寺路666号C棟、武漢、430206
