Anti-LASV GPC Recombinant Antibody (12.1F) (VK453063)

Name: Anti-LASV GPC Recombinant Antibody (12.1F)
Brand: abinScience
SKU: VK453063
Price: 126 USD
Availability: InStock

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Precio(USD):

Especificación:

20ug
50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

VK453063

Reactividad de especies

Lassa virus (LASV)

Aplicaciones

ELISA, Neutralization, WB, FCM

Especie huésped

Human

Clonalidad

Monoclonal

Isotipo

IgG1, kappa

ID de clon

12.1F

Aplicaciones probadas

Objetivo

Pre-glycoprotein polyprotein GP complex, Pre-GP-C, GPC, GP-C

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

P08669

RRID

Anti-LASV GPC Antibody (12.1F) (abinScience Cat# VK453063, RRID:AB_3725214)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Pre-glycoprotein polyprotein GP complex (GPC) is a ~55 kDa protein. Functions as a cleaved signal peptide that is retained as the third component of the GP complex (GP-C). Helps to stabilize the spike complex in its native conformation. The SSP is required for efficient glycoprotein expression, post-translational maturation cleavage of G1 and G2, glycoprotein transport to the cell surface plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion.

1. Katz, M. et al. (2022) Nature 603, 174-179. PMID: 35173332

2. Eichler, R. et al. (2003) EMBO reports 4, 1084-8. PMID: 14555961

Nota

For research use only.

Imágenes

Bioactivity

Detects LASV GPC protein (VK453011) in indirect ELISAs.
Bioactivity

Detects Recombinant LASV GPC Protein, N-His & C-TwinStrep (Cat No.: VK453011) in indirect ELISA.
SDS-PAGE

SDS-PAGE for Anti-LASV GPC Antibody (12.1F).
Western blot

Western blot analysis was performed using anti-Lassa virus GPC monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant LASV GPC (Catalog No: VK453011)