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| カタログ番号 | VK453063 | ||||||
|---|---|---|---|---|---|---|---|
| 種反応性 | Lassa virus (LASV) | ||||||
| アプリケーション | ELISA, Neutralization, WB, FCM | ||||||
| 宿主種 | Human | ||||||
| クローン性 | Monoclonal | ||||||
| アイソタイプ | IgG1, kappa | ||||||
| クローンID | 12.1F | ||||||
| テスト済みアプリケーション | WB | ||||||
| ターゲット | Pre-glycoprotein polyprotein GP complex, Pre-GP-C, GPC, GP-C | ||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||
| 純度 | >95% as determined by SDS-PAGE. | ||||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||||
| アクセッション番号 | P08669 | ||||||
| RRID | Anti-LASV GPC Antibody (12.1F) (abinScience Cat# VK453063, RRID:AB_3725214) |
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| 形態 | Liquid | ||||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| 背景 | Pre-glycoprotein polyprotein GP complex (GPC) is a ~55 kDa protein. Functions as a cleaved signal peptide that is retained as the third component of the GP complex (GP-C). Helps to stabilize the spike complex in its native conformation. The SSP is required for efficient glycoprotein expression, post-translational maturation cleavage of G1 and G2, glycoprotein transport to the cell surface plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion. 1. Katz, M. et al. (2022) Nature 603, 174-179. PMID: 35173332 2. Eichler, R. et al. (2003) EMBO reports 4, 1084-8. PMID: 14555961 | ||||||
| 注意事項 | For research use only. |
Detects LASV GPC protein (VK453011) in indirect ELISAs.
Detects Recombinant LASV GPC Protein, N-His & C-TwinStrep (Cat No.: VK453011) in indirect ELISA.
SDS-PAGE for Anti-LASV GPC Antibody (12.1F).
Western blot analysis was performed using anti-Lassa virus GPC monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant LASV GPC (Catalog No: VK453011)
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