Anti-LASV GPC Recombinant Antibody (25.10C.) (VK453103)

Name: Anti-LASV GPC Recombinant Antibody (25.10C.)
Brand: abinScience
SKU: VK453103
Price: 126 USD
Availability: InStock

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1mg

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

VK453103

Reactivité des espèces

Lassa virus (LASV)

Applications

ELISA, Neutralization

Espèce hôte

Human

Clonalité

Monoclonal

Isotype

IgG1, kappa

ID de clone

25.10C.

Cible

Pre-glycoprotein polyprotein GP complex, Pre-GP-C, GPC, GP-C

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P08669

RRID

Anti-LASV GPC Antibody (25.10C.) (abinScience Cat# VK453103, RRID:AB_3725218)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Pre-glycoprotein polyprotein GP complex (GPC) is a ~55 kDa protein. Functions as a cleaved signal peptide that is retained as the third component of the GP complex (GP-C). Helps to stabilize the spike complex in its native conformation. The SSP is required for efficient glycoprotein expression, post-translational maturation cleavage of G1 and G2, glycoprotein transport to the cell surface plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion.

1. Katz, M. et al. (2022) Nature 603, 174-179. PMID: 35173332

2. Eichler, R. et al. (2003) EMBO reports 4, 1084-8. PMID: 14555961

Note

For research use only.

Images