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| カタログ番号 | HA735014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-LSM6 Polyclonal Antibody (HA735014) is a rabbit polyclonal antibody detecting U6 snRNA-associated Sm-like protein LSm6; LSM6 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human LSM6 (Ser2-Met80). | ||||||||
| ターゲット | U6 snRNA-associated Sm-like protein LSm6; LSM6 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P62312, P62313, Q9M1Z3 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | U6 snRNA-associated Sm-like protein LSm6 is a ~9 kDa protein. Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway (Probable). 1. Bertram, K. et al. (2017) Cell 170, 701-713.e11. PMID: 28781166 2. Achsel, T. et al. (1999) The EMBO journal 18, 5789-802. PMID: 10523320 | ||||||||
| 注意事項 | For research use only |
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