

| Numéro de catalogue | HW356014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-LSS Polyclonal Antibody (HW356014) is a rabbit polyclonal antibody detecting LSS in ELISA, IHC, WB. Suitable for Human, Mouse, and Bovine.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human LSS (Asp388-Pro549). | ||||||||
| Cible | OSC, Lanosterol synthase, hOSC, Oxidosqualene--lanosterol cyclase, 2, 3-epoxysqualene--lanosterol cyclase, LSS | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P48449 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Lanosterol synthase (LSS) is a ~83 kDa protein. Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein aggregation and increase transparency. 1. Ruf, A. et al. (2004) Biochemical and biophysical research communications 315, 247-54. PMID: 14766201 2. Zhao, L. et al. (2015) Nature 523, 607-11. PMID: 26200341 3. Baker, CH. et al. (1995) Biochemical and biophysical research communications 213, 154-60. PMID: 7639730 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-LSS polyclonal antibody at 1ug/mL on various samples.
Lane 1: SH-SY5Y cell lysate
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