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| カタログ番号 | HW356014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-LSS Polyclonal Antibody (HW356014) is a rabbit polyclonal antibody detecting LSS in ELISA, IHC, WB. Suitable for Human, Mouse, and Bovine.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human LSS (Asp388-Pro549). | ||||||||
| ターゲット | OSC, Lanosterol synthase, hOSC, Oxidosqualene--lanosterol cyclase, 2, 3-epoxysqualene--lanosterol cyclase, LSS | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P48449 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Lanosterol synthase (LSS) is a ~83 kDa protein. Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein aggregation and increase transparency. 1. Ruf, A. et al. (2004) Biochemical and biophysical research communications 315, 247-54. PMID: 14766201 2. Zhao, L. et al. (2015) Nature 523, 607-11. PMID: 26200341 3. Baker, CH. et al. (1995) Biochemical and biophysical research communications 213, 154-60. PMID: 7639730 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-LSS polyclonal antibody at 1ug/mL on various samples.
Lane 1: SH-SY5Y cell lysate
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