

| Numéro de catalogue | HF529014 | ||||||||
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| Description |
Anti-LYPLA2 Polyclonal Antibody (HF529014) is a rabbit polyclonal antibody detecting LYPLA2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human LYPLA2 (Met1-Thr196). | ||||||||
| Cible | LYPLA2, APT-2, LysoPLA II, LPL-II, Acyl-protein thioesterase 2, Lysophospholipase II, APT2 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O95372 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Acyl-protein thioesterase 2 (LYPLA2) is a ~24 kDa protein. Acts as an acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GSDMD, GAP43, ZDHHC6 or HRAS. Deacylates GAP43. Mediates depalmitoylation of ZDHHC6. Has lysophospholipase activity. Hydrolyzes prostaglandin glycerol esters (PG-Gs) in the following order prostaglandin D2-glycerol ester (PGD2-G) > prostaglandin E2 glycerol ester (PGE2-G) > prostaglandin F2-alpha-glycerol ester (PGF2-alpha-G). 1. Tomatis, VM. et al. (2010) PloS one 5, e15045. PMID: 21152083 2. Abrami, L. et al. (2017) eLife 6. PMID: 28826475 3. Manna, JD. et al. (2014) The Journal of biological chemistry 289, 33741-53. PMID: 25301951 | ||||||||
| Note | For research use only. |
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