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| カタログ番号 | HF529014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-LYPLA2 Polyclonal Antibody (HF529014) is a rabbit polyclonal antibody detecting LYPLA2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human LYPLA2 (Met1-Thr196). | ||||||||
| ターゲット | LYPLA2, APT-2, LysoPLA II, LPL-II, Acyl-protein thioesterase 2, Lysophospholipase II, APT2 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O95372 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Acyl-protein thioesterase 2 (LYPLA2) is a ~24 kDa protein. Acts as an acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GSDMD, GAP43, ZDHHC6 or HRAS. Deacylates GAP43. Mediates depalmitoylation of ZDHHC6. Has lysophospholipase activity. Hydrolyzes prostaglandin glycerol esters (PG-Gs) in the following order prostaglandin D2-glycerol ester (PGD2-G) > prostaglandin E2 glycerol ester (PGE2-G) > prostaglandin F2-alpha-glycerol ester (PGF2-alpha-G). 1. Tomatis, VM. et al. (2010) PloS one 5, e15045. PMID: 21152083 2. Abrami, L. et al. (2017) eLife 6. PMID: 28826475 3. Manna, JD. et al. (2014) The Journal of biological chemistry 289, 33741-53. PMID: 25301951 | ||||||||
| 注意事項 | For research use only. |
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