

| Каталожный номер | VK765014 | ||||
|---|---|---|---|---|---|
| Описание |
Anti-MACV Nucleoprotein Polyclonal Antibody (VK765014) is a rabbit polyclonal antibody detecting Nucleoprotein in ELISA, IHC, WB. Suitable for Machupo virus.
Highlights
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| Реактивность видов | Machupo virus (MACV), Junin mammarenavirus (JUNV) (Junn mammarenavirus) | ||||
| Применения | ELISA, IHC, WB | ||||
| Хозяинский вид | Rabbit | ||||
| Клоональность | Polyclonal | ||||
| Изотип | IgG | ||||
| Иммуноген | E. coli - derived recombinant MACV Nucleoprotein (Met1-Leu564). | ||||
| Цель | Nucleoprotein, 3.1.13.-, Nucleocapsid protein, Protein N, N | ||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||
| Очистка | Purified by antigen affinity column. | ||||
| Номер доступа | P26578, P14239 | ||||
| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Фон | Nucleoprotein is a ~63 kDa protein. Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation. | ||||
| Примечание | For research use only |
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