

| Каталожный номер | VK765034 | ||||
|---|---|---|---|---|---|
| Описание |
Anti-MACV Z Polyclonal Antibody (VK765034) is a rabbit polyclonal antibody detecting MACV Z in ELISA, IHC, WB. Suitable for Tacaribe virus and Machupo virus.
Highlights
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| Реактивность видов | Junin mammarenavirus (JUNV) (Junn mammarenavirus), Machupo virus (MACV) | ||||
| Применения | ELISA, IHC, WB | ||||
| Хозяинский вид | Rabbit | ||||
| Клоональность | Polyclonal | ||||
| Изотип | IgG | ||||
| Иммуноген | E. coli - derived recombinant MACV Z (Gln15-Pro94). | ||||
| Цель | Z protein, Z protein | ||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||
| Очистка | Purified by antigen affinity column. | ||||
| Номер доступа | Q88470, Q6IVU5, Q6IUF9 | ||||
| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Фон | RING finger protein Z is a ~10 kDa protein. Plays a crucial role in virion assembly and budding. Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L. Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP. Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway. The budding of the virus progeny occurs after association of protein Z with the viral glycoprotein complex SSP-GP1-GP2 at the cell periphery, step that requires myristoylation of protein Z. 1. Jácamo, R. et al. (2003) Journal of virology 77, 10383-93. PMID: 12970423 | ||||
| Примечание | For research use only |
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