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Anti-Magnaporthe oryzae ATG8 Polyclonal Antibody (JN177014)

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Número de catálogoJN177014
Descripción
Anti-Magnaporthe oryzae ATG8 Polyclonal Antibody (JN177014) is a rabbit polyclonal antibody detecting ATG8. Suitable for Phaeosphaeria nodorum, Sclerotinia sclerotiorum, Aspergillus oryzae, Coccidioides immitis, Glomerella lagenarium, Aspergillus fumigatus, Pyricularia oryzae, Colletotrichum lindemuthianum, Neurospora crassa, Aspergillus terreus, Gibberella zeae, Penicillium rubens, Botryotinia fuckeliana, Beauveria bassiana, Neosartorya fischeri, Aspergillus clavatus, Podospora anserina, Emericella nidulans, Cochliobolus heterostrophus, Chaetomium globosum, and Aspergillus niger.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesPhaeosphaeria nodorum, Sclerotinia sclerotiorum, Aspergillus oryzae, Aspergillus niger
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Magnaporthe oryzae ATG8 (Met1-Phe115).
Objetivo ATG8, Autophagy-related protein 8, Autophagy-related ubiquitin-like modifier ATG8
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso Q51MW4
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

Autophagy-related protein 8 (ATG8) is a ~14 kDa protein. Ubiquitin-like modifier involved in autophagosome formation. With ATG4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.

Nota For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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