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Anti-MAP3K1 Polyclonal Antibody (HC601014)

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Vista general
Número de catálogoHC601014
Descripción
Anti-MAP3K1 Polyclonal Antibody (HC601014) is a rabbit polyclonal antibody detecting MAP3K1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human MAP3K1 (Ile1307-Arg1509).
Objetivo MAPK/ERK kinase kinase 1, Mitogen-activated protein kinase kinase kinase 1, MAP3K1, MEKK 1, MEKK, MEK kinase 1, MAPKKK1, MEKK1
Purificación Purified by antigen affinity column.
Número de acceso Q13233
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Mitogen-activated protein kinase kinase kinase 1 (MAP3K1) is a ~164 kDa protein. Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. May phosphorylate the MAPK8/JNK1 kinase. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway.

1. Xia, Y. et al. (1998) Genes & development 12, 3369-81. PMID: 9808624
2. Ye, B. et al. (2007) FEBS letters 581, 4403-10. PMID: 17761173
Nota For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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