

| Numéro de catalogue | HV738014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human MAP3K5 (Gly681-Glu936). | ||||||||
| Cible | ASK1, MAPK/ERK kinase kinase 5, MEKK5, MAPKKK5, MEKK 5, Apoptosis signal-regulating kinase 1, ASK-1, Mitogen-activated protein kinase kinase kinase 5, MAP3K5, MEK kinase 5 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q99683 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Mitogen-activated protein kinase kinase kinase 5 (MAP3K5) is a ~154 kDa protein. Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signaling for determination of cell fate such as differentiation and survival. Plays a crucial role in the apoptosis signal transduction pathway through mitochondria-dependent caspase activation. MAP3K5/ASK1 is required for the innate immune response, which is essential for host defense against a wide range of pathogens. | ||||||||
| Note | For research use only. |
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