Anti-MAPK11 Polyclonal Antibody (HS729014)

Name: Anti-MAPK11 Polyclonal Antibody
Brand: abinScience
SKU: HS729014
Price: 168 USD
Availability: InStock

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Обзор

Каталожный номер

HS729014

Описание

Anti-MAPK11 Polyclonal Antibody (HS729014) is a rabbit polyclonal antibody detecting MAPK11 in ELISA, IHC, WB. Suitable for Human and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human, Mouse

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human MAPK11 (Leu24-Phe308).

Цель

MAP kinase 11, Mitogen-activated protein kinase p38 beta, MAPK 11, Mitogen-activated protein kinase 11, PRKM11, SAPK2B, Stress-activated protein kinase 2b, MAP kinase p38 beta, MAPK11, p38b, p38-2, SAPK2, SAPK2b

Очистка

Purified by antigen affinity column.

Номер доступа

Q15759

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Mitogen-activated protein kinase 11 (MAPK11) is a ~41 kDa protein. Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK11 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as pro-inflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. MAPK11 functions are mostly redundant with those of MAPK14. Some of the targets are downstream kinases which are activated through phosphorylation and further phosphorylate additional targets.

1. Shi, Y. et al. (2002) Biological chemistry 383, 1519-36. PMID: 12452429

2. Cuadrado, A. et al. (2010) The Biochemical journal 429, 403-17. PMID: 20626350

3. Robinson, KS. et al. (2022) Science (New York, N.Y.) 377, 328-335. PMID: 35857590

4. Deak, M. et al. (1998) The EMBO journal 17, 4426-41. PMID: 9687510

5. Scheper, GC. et al. (2001) Molecular and cellular biology 21, 743-54. PMID: 11154262

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-MAPK11 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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