Anti-MAPRE1 Polyclonal Antibody (HS950014)

Name: Anti-MAPRE1 Polyclonal Antibody
Brand: abinScience
SKU: HS950014
Price: 168 USD
Availability: InStock

データシート製品共有情報コピー

価格(USD):

スペック:

50ug
100ug

数量:

お問い合わせ

概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HS950014

説明

Anti-MAPRE1 Polyclonal Antibody (HS950014) is a rabbit polyclonal antibody detecting MAPRE1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Coturnix coturnix.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human, Mouse, Rat

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human MAPRE1 (Ala2-Tyr268).

ターゲット

EB1, Microtubule-associated protein RP/EB family member 1, MAPRE1, APC-binding protein EB1, End-binding protein 1

精製

Purified by antigen affinity column.

アクセッション番号

Q15691

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Microtubule-associated protein RP/EB family member 1 (MAPRE1) is a ~29 kDa protein. Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Recruits other +TIP proteins to microtubules by binding to a conserved Ser-X-Leu-Pro (SXLP) motif in their polypeptide chains. Promotes cytoplasmic microtubule nucleation and elongation. Involved in mitotic spindle positioning by stabilizing microtubules and promoting dynamic connection between astral microtubules and the cortex during mitotic chromosome segregation. Assists chromosome alignment in metaphase by recruiting the SKA complex to the spindle and stabilizing its interactions with microtubule bundles (K-fibers).

1. Askham, JM. et al. (2002) Molecular biology of the cell 13, 3627-45. PMID: 12388762

2. Hayashi, I. et al. (2005) Molecular cell 19, 449-60. PMID: 16109370

3. Honnappa, S. et al. (2009) Cell 138, 366-76. PMID: 19632184

4. van der Vaart, B. et al. (2011) The Journal of cell biology 193, 1083-99. PMID: 21646404

5. Xia, P. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 16564-9. PMID: 23001180

6. Wei, J. et al. (2017) FEBS letters 591, 2379-2393. PMID: 28726242

7. Yang, C. et al. (2017) The Journal of cell biology 216, 3179-3198. PMID: 28814570

8. Song, X. et al. (2021) Nature chemical biology 17, 1314-1323. PMID: 34608293

9. Radhakrishnan, RM. et al. (2023) The Journal of biological chemistry 299, 102853. PMID: 36592928

注意事項

For research use only.

イメージ

参考文献

データシート

Anti-MAPRE1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-MAPRE1 Polyclonal Antibody (HS950014)

概要

イメージ

参考文献

データシート

SDS

クイックアクセス

お問い合わせ