Anti-MARV Glycoprotein GP1 Recombinant Antibody (MR78) (VK669023)

Name: Anti-MARV Glycoprotein GP1 Recombinant Antibody (MR78)
Brand: abinScience
SKU: VK669023
Price: 126 USD
Availability: InStock

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Precio(USD):

Especificación:

20ug
50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

VK669023

Reactividad de especies

Lake Victoria marburgvirus (MARV) (Marburg virus), Zaire ebolavirus (ZEBOV) (Zaire Ebola virus)

Aplicaciones

ELISA

Especie huésped

Human

Clonalidad

Monoclonal

Isotipo

IgG1

ID de clon

MR78

Objetivo

Envelope glycoprotein, GP1, 2, GP, Virion spike glycoprotein, GP1, GP2, GP

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

Q1PDC7

RRID

Anti-MARV GP/Envelope glycoprotein Antibody (MR78) (abinScience Cat# VK669023, RRID:AB_3727017)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Reconstitución

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Envelope glycoprotein (GP) is a ~75 kDa protein. GP1 is responsible for binding to the receptor(s) on target cells. Interacts with CD209/DC-SIGN and CLEC4M/DC-SIGNR which act as cofactors for virus entry into the host cell. Binding to CD209 and CLEC4M, which are respectively found on dendritic cells (DCs), and on endothelial cells of liver sinusoids and lymph node sinuses, facilitate infection of macrophages and endothelial cells. These interactions not only facilitate virus cell entry, but also allow capture of viral particles by DCs and subsequent transmission to susceptible cells without DCs infection (trans infection).

Nota

For research use only.

Imágenes