Anti-MARV Glycoprotein GP1 Recombinant Antibody (MR78) (VK669023)

Name: Anti-MARV Glycoprotein GP1 Recombinant Antibody (MR78)
Brand: abinScience
SKU: VK669023
Price: 126 USD
Availability: InStock

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20ug
50ug
100ug
1mg

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

VK669023

Reactivité des espèces

Lake Victoria marburgvirus (MARV) (Marburg virus), Zaire ebolavirus (ZEBOV) (Zaire Ebola virus)

Applications

ELISA

Espèce hôte

Human

Clonalité

Monoclonal

Isotype

IgG1

ID de clone

MR78

Cible

Envelope glycoprotein, GP1, 2, GP, Virion spike glycoprotein, GP1, GP2, GP

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q1PDC7

RRID

Anti-MARV GP/Envelope glycoprotein Antibody (MR78) (abinScience Cat# VK669023, RRID:AB_3727017)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Envelope glycoprotein (GP) is a ~75 kDa protein. GP1 is responsible for binding to the receptor(s) on target cells. Interacts with CD209/DC-SIGN and CLEC4M/DC-SIGNR which act as cofactors for virus entry into the host cell. Binding to CD209 and CLEC4M, which are respectively found on dendritic cells (DCs), and on endothelial cells of liver sinusoids and lymph node sinuses, facilitate infection of macrophages and endothelial cells. These interactions not only facilitate virus cell entry, but also allow capture of viral particles by DCs and subsequent transmission to susceptible cells without DCs infection (trans infection).

Note

For research use only.

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