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| カタログ番号 | VK669023 | ||||
|---|---|---|---|---|---|
| 種反応性 | Lake Victoria marburgvirus (MARV) (Marburg virus), Zaire ebolavirus (ZEBOV) (Zaire Ebola virus) | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Human | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG1 | ||||
| クローンID | MR78 | ||||
| ターゲット | Envelope glycoprotein, GP1, 2, GP, Virion spike glycoprotein, GP1, GP2, GP | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q1PDC7 | ||||
| RRID | Anti-MARV GP/Envelope glycoprotein Antibody (MR78) (abinScience Cat# VK669023, RRID:AB_3727017) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||
| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Envelope glycoprotein (GP) is a ~75 kDa protein. GP1 is responsible for binding to the receptor(s) on target cells. Interacts with CD209/DC-SIGN and CLEC4M/DC-SIGNR which act as cofactors for virus entry into the host cell. Binding to CD209 and CLEC4M, which are respectively found on dendritic cells (DCs), and on endothelial cells of liver sinusoids and lymph node sinuses, facilitate infection of macrophages and endothelial cells. These interactions not only facilitate virus cell entry, but also allow capture of viral particles by DCs and subsequent transmission to susceptible cells without DCs infection (trans infection). | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-MARV GP/Envelope glycoprotein Antibody (MR78).
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