

| Número de catálogo | VK073034 | ||||||||
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| Descripción |
Anti-MERS-CoV ORF4b Polyclonal Antibody (VK073034) is a rabbit polyclonal antibody detecting Non-structural protein ORF4b; ORF4b; ORF4b in ELISA, IHC, WB.
Highlights
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| Reactividad de especies | Middle East respiratory syndrome-related coronavirus (MERS-CoV) | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant mers-cov ORF4b (Met1-Phe246(Pro44His)). | ||||||||
| Objetivo | Non-structural protein ORF4b; ORF4b; ORF4b | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | K9N643 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Non-structural protein ORF4b is a ~28 kDa protein. Plays a role in the inhibition of host innate immunity by inhibiting the interaction between host IKBKE and MAVS. In turn, this inhibition prevents the production of host interferon beta. Additionally, inhibits host NF-kappa-B by interacting with host KPNA4 and thereby preventing the translocation of the NF-kappa-B complex into the nucleus by this importin. 1. Canton, J. et al. (2018) PLoS pathogens 14, e1006838. PMID: 29370303 | ||||||||
| Nota | For research use only |
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