

| Numéro de catalogue | VK073034 | ||||||||
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| Description |
Anti-MERS-CoV ORF4b Polyclonal Antibody (VK073034) is a rabbit polyclonal antibody detecting Non-structural protein ORF4b; ORF4b; ORF4b in ELISA, IHC, WB.
Highlights
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| Reactivité des espèces | Middle East respiratory syndrome-related coronavirus (MERS-CoV) | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant mers-cov ORF4b (Met1-Phe246(Pro44His)). | ||||||||
| Cible | Non-structural protein ORF4b; ORF4b; ORF4b | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | K9N643 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Non-structural protein ORF4b is a ~28 kDa protein. Plays a role in the inhibition of host innate immunity by inhibiting the interaction between host IKBKE and MAVS. In turn, this inhibition prevents the production of host interferon beta. Additionally, inhibits host NF-kappa-B by interacting with host KPNA4 and thereby preventing the translocation of the NF-kappa-B complex into the nucleus by this importin. 1. Canton, J. et al. (2018) PLoS pathogens 14, e1006838. PMID: 29370303 | ||||||||
| Note | For research use only |
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