

| カタログ番号 | VK073034 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-MERS-CoV ORF4b Polyclonal Antibody (VK073034) is a rabbit polyclonal antibody detecting Non-structural protein ORF4b; ORF4b; ORF4b in ELISA, IHC, WB.
Highlights
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| 種反応性 | Middle East respiratory syndrome-related coronavirus (MERS-CoV) | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant mers-cov ORF4b (Met1-Phe246(Pro44His)). | ||||||||
| ターゲット | Non-structural protein ORF4b; ORF4b; ORF4b | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | K9N643 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Non-structural protein ORF4b is a ~28 kDa protein. Plays a role in the inhibition of host innate immunity by inhibiting the interaction between host IKBKE and MAVS. In turn, this inhibition prevents the production of host interferon beta. Additionally, inhibits host NF-kappa-B by interacting with host KPNA4 and thereby preventing the translocation of the NF-kappa-B complex into the nucleus by this importin. 1. Canton, J. et al. (2018) PLoS pathogens 14, e1006838. PMID: 29370303 | ||||||||
| 注意事項 | For research use only |
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