

| Número de catálogo | ZA029033 | ||||
|---|---|---|---|---|---|
| Reactividad de especies | Centruroides (Mexican scorpion) | ||||
| Aplicaciones | ELISA, Neutralization, SPR | ||||
| Especie huésped | Mouse | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | IgG2a | ||||
| ID de clon | 11F | ||||
| Objetivo | Beta-toxin Cl13, CliNaTxBet37, Beta-toxin Cb3, Centruroides limpidus (Mexican scorpion), Centruroides baergi (Scorpion) (Centruroides nigrovariatus baergi) | ||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||
| Pureza | >95% as determined by SDS-PAGE. | ||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||
| Número de acceso | C0HK69, C0HLR5 | ||||
| RRID | Anti-Mexican scorpion Beta-toxin Cl13/Cb3 Antibody (11F) (abinScience Cat# ZA029033, RRID:AB_3729012) |
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| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Fondo | Beta-toxin Cl13 (Cb3) is a ~8 kDa protein. Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. Inhibits sodium channels Nav1.4/SCN4A, Nav1.5/SCN5A and Nav1.6/SCN8A. Also has a weak inhibitory effect on Nav1.2/SCN2A. Is lethal to mice. 1. Olamendi-Portugal, T. et al. (2017) Peptides 87, 34-40. PMID: 27871874 | ||||
| Nota | For research use only. |

SDS-PAGE for Anti-Mexican scorpion Beta-toxin Cl13/Cb3 Antibody (11F)
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